Key Publications
- Seymour, R. A., Alexander, N., & Maguire, E. A. (2022). Robust estimation of 1/f activity improves oscillatory burst detection. European Journal of Neuroscience, 1– 17.
An improved method for detecting oscillatory bursts by estimating background 1/f activity more accurately.
- Seymour, R. A., Alexander, N., Mellor, S., O’Neill, G. C., Tierney, T. M., Barnes, G. R., & Maguire, E. A. (2021). Interference suppression techniques for OPM-based MEG: Opportunities and challenges. NeuroImage, 118834.
A tutorial-based review on issues with interference (noise) in wearable OPM-MEG recordings and how to fix these issues. We focus on software-based interference suppression and include two detailed tutorials.
- Seymour, R. A., Alexander, N., Mellor, S. J., O’Neill, G. C., Tierney, T. M., Barnes, G. R., & Maguire, E. A. (2021). Using OPMs to measure neural activity in standing, mobile participants. Neuroimage.
We show how wearable OPM-MEG can be used to measure neural activity while participants are standing and freely moving their head.
- Seymour, R. A., Rippon, G., Gooding-Williams, G., Sowman, P. F., & Kessler, K. (2020). Reduced auditory steady state responses in autism spectrum disorder. Molecular autism, 11(1), 1-13.
Using MEG we show that autistic adolescents have reduced auditory steady-state responses at 40 Hz.
- Seymour, R. A., Rippon, G., Gooding-Williams, G., Schoffelen, J. M., & Kessler, K. (2019). Dysregulated oscillatory connectivity in the visual system in autism spectrum disorder. Brain, 142(10), 3294-3305.
Visual connectivity was examined in autistic adolescents using a simple grating stimulus. We found both reduced feedback connectivity and dysregulated local processing. Our results have implications for sensory sensitivities in autism and link to predictive-coding accounts of perception.
- Seymour, R. A., Rippon, G., & Kessler, K. (2017). The Detection of Phase Amplitude Coupling during Sensory Processing. Frontiers in neuroscience, 11, 487.
Various methods for measuring Phase Amplitude Coupling (PAC) are reviewed and compared using simulated data and real MEG recordings. Practical recommendations for PAC analyis are given.
- Kessler, K., Seymour, R. A., & Rippon, G. (2016). Brain oscillations and connectivity in autism spectrum disorders (ASD): new approaches to methodology, measurement and modelling. Neuroscience & Biobehavioral Reviews, 71, 601-620.